Non-bailable warrants were issued by a district court in Thane to Vicky Goswami, the alleged international drug-lord and his partner and Bollywood actor Mamta Kulkarni in an ephedrine haul case.
Both are believed to be outside India.
District Judge H M Patwardhan issued the warrants on Tuesday.
Thane police raided Avon Lifesciences in Solapur in 2016 and seized around 18.5 tonne of ephedrine worth Rs 2,000 crore.
As per the police, ephedrine was being diverted from Avon Lifesciences to a Kenya-based drug cartel headed by Goswami where it was used to make party-drug Methamphetamine.
The police have arrested more than 10 persons in the case.