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Low birth weight may lead to higher chances of developing type 2 diabetes

A New Study Has Found That People Born With A Low Birth Weight Due To Genetic Factors May Have An Increased Risk Of Developing Type 2 Diabetes. Researchers Created A Genetic Risk Score (GRS) Based On Five Low Birth Weight-related Genetic Variations Known As Single Nucleotide Polymorphisms (SNPs).

News Nation Bureau | Edited By : Hina Khan | Updated on: 26 Jun 2016, 07:21:49 PM
Low birth weight may lead to higher chances of developing type 2 diabetes

New Delhi:

A new study has found that people born with a low birth weight due to genetic factors may have an increased risk of developing type 2 diabetes. Researchers created a genetic risk score (GRS) based on five low birth weight-related genetic variations known as single nucleotide polymorphisms (SNPs).

Their analysis showed that for each one point increase in GRS (with the score ranging from 1-10), the risk of developing type 2 diabetes increased by six per cent.

Researchers from Tulane University in the US conducted the study on 3,627 type 2 diabetes cases and 12,974 controls of European ancestry. Further evidence found that low birth-weight was actually causing the excess risk in type 2 diabetes.

“Evidence from both population and experimental studies has suggested that restricted early life development has long-term structural and functional influence on individuals' predisposition to an increased risk of metabolic diseases such as type 2 diabetes,” researchers said.

As low-birth weight represents restricted foetal growth. In the research it was found that a genetically lowered birth weight was associated with increased susceptibility to type 2 diabetes.

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First Published : 26 Jun 2016, 07:09:00 PM

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