New Delhi:
In a breakthrough research, UK scientists have identified a protein that acts as an "exercise sensor" which help in detect changes in the blood flow during exercise, according to the research published in Nature Communications.
Through this findings, a person doesn't require to break a sweat and this pill will offer a workout benefits.
During the physical activity, the heart pumps more blood in the body the Piezo1 protein in the endothelium or lining of the arteries senses the increased pressure on the wall of the blood vessels, the new research found.
And it slightly alters the electrical balance in the endothelium and this results in the blood vessels constricting.
Modifying Piezo1 protein in the intestines can help us move a step closer to having a drug that can help control cardiometabolic syndromes such as cardiovascular disease and Type 2 diabetes, the researchers said.
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"If we can understand how these systems work, then we may be able to develop techniques that can help tackle some of the biggest diseases afflicting modern societies,” said lead researcher David Beech, a professor at the University of Leeds in the UK.
“We know that exercise can protect against heart disease, stroke, and many other conditions. This study has identified a physiological system that senses when the mammalian body is exercising,” Beech added.
The researchers are also keen to investigate the impact of an experimental compound called Yoda1 on the action of the Piezo1 protein.
Researchers have found that same level of pressure is exerted on the walls of endothelium which is experienced during physical activity and which ultimately raising the possibility that a drug could be developed which enhances the health benefits of exercise.
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