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Life on Earth: RNA can decode the unsolved mystery

Scientists Have Long Wondered About The Origin Of These Biological Compounds. Some Of Them Believe That The Earth Was Seeded By Comets Or Asteroids That Contained The Basic Building Blocks Needed To Form Such Molecules.

PTI | Updated on: 12 Apr 2016, 04:36:18 PM
Life on Earth (Representative image)


Scientists have for the first time shown that one of the building blocks of genetic material in living organisms may have formed in cometary ices, suggesting that comets could be source of the organic molecules that made life possible on Earth. To obtain this result, scientists at the National Centre for Scientific Research in France (CNRS) created an artificial comet and carried out a highly detailed analysis. They propose the first realistic scenario for the formation of this key compound, which had never been detected in meteorites or cometary ices until now.

The genetic material of all living organisms on Earth, as well as of viruses, is made up of nucleic acids, DNA and RNA. RNA, which is considered more primitive, is thought to have been one of the first molecules characteristic of life to appear on Earth. Scientists have long wondered about the origin of these biological compounds. Some of them believe that the Earth was seeded by comets or asteroids that contained the basic building blocks needed to form such molecules.

Several amino acids (the components of proteins) and nitrogenous bases (one of the components of nucleic acids) have already been found in meteorites, as well as in artificial comets produced in the laboratory. However, ribose, the other key component of RNA, had never yet been detected in extraterrestrial material or created in the laboratory under ‘astrophysical’ conditions. By simulating the evolution of the interstellar ice making up comets, researchers successfully obtained ribose, a key step in understanding the origin of RNA - and therefore of life.

As a first step, an artificial comet was produced. By placing a representative mixture of water (H2O), methanol (CH3OH) and ammonia (NH3) in a high vacuum chamber at minus 200 degrees Celsius, the researchers simulated the formation of dust grains coated with ice, the raw material of comets. This material was irradiated with UV, as in the molecular clouds where these grains form. The sample was then warmed to room temperature, as in comets when they approach the Sun.

Its composition was analysed, optimising an extremely sensitive and accurate method (multidimensional gas chromatography coupled with time-of-flight mass spectrometry). Several sugars were detected, including ribose. Their diversity and relative abundances suggest that they were formed from formaldehyde (a molecule found in space and on comets that forms in large quantities from methanol and water).

Although the existence of ribose in real comets remains to be confirmed, this discovery completes the list of the molecular building blocks of life that can be formed in interstellar ice. It also lends further support to the theory that comets are the source of the organic molecules that made life possible on Earth, and perhaps elsewhere in the universe. The study was published in the journal Science. 

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First Published : 11 Apr 2016, 06:42:00 PM

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