A NASA report has put India's financial Capital-Mumbai and the chief port city of Karnataka-Mangalore, as a result of melting ice caps.
The list also includes cities like New York and London.
NASA has developed a new simulation technology that can reportedly identify and predict which cities will be affected as different portions of ice sheets are melting due to global warming.
The tool looks at the Earth's spin and gravitational effects to predict how water will be "redistributed" globally.
"As cities and countries attempt to build plans to mitigate flooding, they have to be thinking about 100 years in the future and they want to assess risk in the same way that insurance companies do," said Erik Ivins, senior scientist at NASA's Jet Propulsion Laboratory in the US.